| 产品编号 | bs-9566R-Bio |
| 英文名称 | Rabbit Anti-Osteocrin/Biotin Conjugated antibody |
| 中文名称 | 生物素标记的肌肉素抗体 |
| 别 名 | Musclin; OSTN; OSTN_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 干细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, ) |
| 产品应用 | ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 3.2kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Osteocrin (83-133) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: Musclin, also designated osteocrin (Ostn), shows no homology with any known genes, except that it contains two conserved sequence motifs homologous to the natriuretic peptide family. Musclin is highly expressed in cells of osteoblast lineage and in skeletal muscle tissue, where it is tightly regulated by nutritional changes. It is secreted as either a full-length precursor protein or a processed form. A novel skeletal muscle-derived secretory factor, Musclin may play a role in bone formation and be linked to glucose metabolism. Studies indicate that insulin increases Musclin expression, whereas epinephrine, isoproterenol and forskolin reduce its expression. Musclin is expressed in osteoblasts and young osteocytes. In mouse tissues, expression is bone-specific, although minimal Musclin expression is also observed in muscle, kidney, testis and heart tissues. Function: Appears to modulate osteoblastic differentiation. Could also function as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle. Subcellular Location: Secreted. Tissue Specificity: Expressed in bone. Database links: Entrez Gene: 344901 Human Entrez Gene: 239790 Mouse Omim: 610280 Human SwissProt: P61366 Human SwissProt: P61364 Mouse SwissProt: Q149W1 Mouse Unigene: 526794 Human Unigene: 390880 Mouse Unigene: 29193 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
