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Rabbit Anti-PCDH18/BF488 Conjugated antibody (bs-11112R-BF488)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11112R-BF488
英文名称1 Rabbit Anti-PCDH18/BF488 Conjugated antibody
中文名称 BF488标记的原钙粘附蛋白18抗体
别    名 PCD18_HUMAN; PCDH18; PCDH68L; protocadherin 18; protocadherin 68-like protein; Protocadherin-18.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  信号转导  细胞粘附分子  细胞外基质  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 123kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDH18
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH18 (protocadherin 18), also known as PCDH68L, is a 1,135 amino acid single-pass type I cell membrane protein that contains six cadherin domains and a cytoplasmic tail that differs from classical cadherins. Expressed ubiquitously with highest expression in ovary and lung, PCDH18 interacts with Dab1 and functions as a potential calcium-dependent adhesion protein that may be involved in the establishment of cell-cell connections in the brain. Multiple isoforms of PCDH18 exist due to alternative splicing events.

Function:
Potential calcium-dependent cell-adhesion protein.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed in all tissues, with highest expression in lung and ovary.

Similarity:
Contains 6 cadherin domains.

Database links:

Entrez Gene: 54510 Human

SwissProt: Q9HCL0 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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