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Rabbit Anti-NEGR1/PE-Cy7 Conjugated antibody (bs-11095R-PE-Cy7)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11095R-PE-Cy7
英文名称1 Rabbit Anti-NEGR1/PE-Cy7 Conjugated antibody
中文名称 PE-Cy7标记的神经生长调节蛋白1抗体
别    名 A kindred of IgLON; DMML2433; IgLON family member 4; IGLON4; KILON; Neuronal growth regulator 1; Neurotractin; Ntra; PRO4993; UNQ2433; NEGR1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 发育生物学  神经生物学  细胞粘附分子  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NEGR1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
NEGR1 is a 354 amino acid protein belonging to the IgLON family and immunoglobulin superfamily. NEGR1 may play a role in cell adhesion and regenerative axon sprouting in the mammalian brain and is highly expressed in adult hippocampus, cerebrum and brainstem, with much lower levels found in cerebellum. Localizing to the cell membrane at the glycosylphosphatidylinositol anchor (GPI) anchor, NEGR1 contains three Ig-like C2-type (immunoglobulin-like) domains. NEGR1 is encoded by a gene that maps to human chromosome 1p31.1, and is one of several loci associated with body mass index (BMI), possibly contributing to the development of obesity.

Function:
NEGR1 may be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor

Similarity:
Belongs to the immunoglobulin superfamily. IgLON family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.

Database links:

Entrez Gene: 257194 Human

Entrez Gene: 320840 Mouse

Entrez Gene: 59318 Rat

Omim: 613173 Human

SwissProt: Q7Z3B1 Human

SwissProt: D3Z4T6 Mouse

SwissProt: D4A2V0 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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