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Rabbit Anti-PCDH7/BF594 Conjugated antibody (bs-11085R-BF594)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11085R-BF594
英文名称1 Rabbit Anti-PCDH7/BF594 Conjugated antibody
中文名称 BF594标记的原钙粘蛋白7抗体
别    名 BH Pcdh; BH protocadherin; BH-Pcdh; BHPCDH; Brain heart protocadherin; Brain-heart protocadherin; PCDH 7; PCDH7; PCDH-7; PCDH7_HUMAN; Protocadherin 7; Protocadherin7; Protocadherin-7.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  信号转导  细胞粘附分子  细胞骨架  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 113kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDH7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
As a subfamily of the cadherin superfamily, protocadherins are cadherin-like cell adhesion proteins that contain up to seven extracellular domains and are predominantly expressed in the nervous system. Importantly, the adhesion mechanism of protocadherins is distinct from classic cadherins. Through inactivation or overexpression, several protocadherins have been implicated in a variety of cancers. PCDH7 (protocadherin 7), also known as BHPCDH or BH-Pcdh, is a 1069 amino acid single-pass I membrane protein that is expressed in the brain and heart. Containing seven cadherin domains, PCDH7 is thought to function in cell-cell recognition and adhesion. PCDH7 exists as three isoforms due to alternative splicing events.

Function:
Expressed predominantly in brain and heart and at lower levels in various other tissues.

Subcellular Location:
Cell membrane.

Post-translational modifications:
Isoform C is phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 7 cadherin domains.

Database links:

Entrez Gene: 488843 Dog

Entrez Gene: 5099 Human

Entrez Gene: 54216 Mouse

Omim: 602988 Human

SwissProt: O60245 Human

Unigene: 479439 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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