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Rabbit Anti-alpha Internexin/BF350 Conjugated antibody (bs-2408R-BF350)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-2408R-BF350
英文名称 Rabbit Anti-alpha Internexin/BF350 Conjugated antibody
中文名称 BF350标记的α-中连蛋白抗体
别    名 a-Internexin; Alpha-Internexin; Alpha-Internexin; 66 kDa neurofilament protein; Alpha Inx; INA; Internexin neuronal intermediate filament protein alpha; MGC12702; NEF 5; NEF5; Neurofilament 5 (66kD); Neurofilament 66; Neurofilament 66 tax binding protein; NF 66; NF66; NF-66; TXBP 1; TXBP1; AINX_HUMAN; Alpha-Inx; Neurofilament-66.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  干细胞  细胞粘附分子  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NF-66
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
eurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009]

Function:
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.

Subcellular Location:
Cytoplasmic.

Tissue Specificity:
Found predominantly in adult CNS.

Post-translational modifications:
O-glycosylated (By similarity).
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the intermediate filament family.

Database links:

Entrez Gene: 9118 Human

Entrez Gene: 226180 Mouse

Entrez Gene: 24503 Rat

Omim: 605338 Human

SwissProt: Q16352 Human

SwissProt: P46660 Mouse

SwissProt: P23565 Rat

Unigene: 500916 Human

Unigene: 276251 Mouse

Unigene: 88941 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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