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Rabbit Anti-Interferon alpha 2b/AF594 Conjugated antibody (bs-0536R-AF594)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-0536R-AF594
英文名称 Anti-Interferon alpha 2b/AF594
中文名称 AF594标记的干扰素α2b抗体
别    名 Interferon alpha-2b; Alpha 2a interferon; alpha-2a interferon; IFN alpha 2b; IFNA 2; IFNA; INFA 2; INFA2; Interferon alpha 2; Interferon alpha 2 precursor; Interferon alpha 8 precursor; Interferon alpha A; Interferon alpha B; Interferon alpha B2; Interferon alpha-2 precursor; LeIF A; LeIF B; LeIFA; MGC125764; Interferon alpha B; Interferon alpha B2; interferon, alpha 8; LeIF B; MGC125765; IFN-alpha-2; IFNA2_HUMAN; MGC125765.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  糖蛋白  细胞因子  干扰素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, 
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 19kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IFN alpha 2b
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Interferon alpha 2b is one of the known 23 different variants of IFN-alpha. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
Interferon alpha 2b is a potent immune modulator. It can either inhibit or enhance immune cell activity within the tightly regulated microenvironment of inflammation, depending upon the concentration of the cytokine and the activation stage of the cell. Interferon alpha 2B is currently used as an anticancer drug due to it's antiproliferative activity.

Function:
Produced by macrophages, IFN-alpha have antiviral activities.

Subunit:
Interacts with IFNAR2.

Subcellular Location:
Secreted.

Similarity:
Belongs to the alpha/beta interferon family.

Database links:

Entrez Gene: 3440 Human

Omim: 147562 Human

SwissProt: P01563 Human

Unigene: 211575 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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