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Rabbit Anti-SERBP1/FITC Conjugated antibody (bs-6734R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6734R-FITC
英文名称1 Rabbit Anti-SERBP1/FITC Conjugated antibody
中文名称 FITC标记的纤溶酶原激活物抑制剂1 RNA结合蛋白抗体
别    名 CGI 55; CHD3IP; Chromodomain helicase DNA binding protein 3 interacting protein; HABP4L; PAI 1 mRNA binding protein; PAI RBP1; PAIRBP1; Plasminogen activator inhibitor 1 RNA binding protein; SERPINE1 mRNA binding protein 1; PAIRB_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  信号转导  肿瘤细胞生物标志物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SERBP1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
SERBP1 (Plasminogen activator inhibitor 1 RNA-binding protein) may play a role in the regulation of mRNA stability. SERBP1 binds to the 3’-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. SERBP1 interacts with CHD3 and is localized in cytoplasmic and nuclear. It is expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.

Function:
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.

Subunit:
Interacts with CHD3 and TDRD3.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasm, perinuclear region.

Tissue Specificity:
Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.

Database links:

Entrez Gene: 26135 Human

Entrez Gene: 66870 Mouse

Entrez Gene: 246303 Rat

Omim: 607378 Human

SwissProt: Q8NC51 Human

SwissProt: Q9CY58 Mouse

SwissProt: Q6AXS5 Rat

Unigene: 530412 Human

Unigene: 240490 Mouse

Unigene: 440861 Mouse

Unigene: 203108 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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