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Rabbit Anti-SDF4/PE Conjugated antibody (bs-6732R-PE)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6732R-PE
英文名称 Rabbit Anti-SDF4/PE Conjugated antibody
中文名称 PE标记的基质细胞衍生因子4抗体(钙结合蛋白)
别    名 CAB45; Calcium binding protein; PSEC0034; SDF 4; SDF-4; Stromal cell derived factor 4; CAB45_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  生长因子和激素  结合蛋白  肿瘤细胞生物标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Horse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SDF4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium dependent cellular activities. [provided by RefSeq, Sep 2011].

Function:
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment (By similarity).
Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini. [COFACTOR] Binds calcium (By similarity). Isoform 5 binds calcium.

Subunit:
Isoform 5 interacts with STXBP1; the interaction is enhanced in presence of calcium. Isoform 5 interacts with STX3.

Subcellular Location:
Isoform 1: Golgi apparatus lumen (By similarity).
Isoform 5: Cytoplasm. Cell projection, bleb. Note=Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs.

Tissue Specificity:
Ubiquitous. Isoform 5 is expressed in pancreas.

Similarity:
Belongs to the CREC family.
Contains 6 EF-hand domains.

Database links:
UniProtKB/Swiss-Prot: Q9BRK5.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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