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Rabbit Anti-HOXA9/AF488 Conjugated antibody (bs-6667R-AF488)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6667R-AF488
英文名称 Anti-HOXA9/AF488
中文名称 AF488标记的同源盒蛋白HOXA9抗体
别    名 ABD-B; Abd-B, drosophila, homolog of; D6a9; Homeobox protein A9; Homeobox 1G; Homeobox A9; Homeobox protein Hox-1.7; Homeobox protein Hox-1G; Homeobox protein Hox-A9; Hox-1.7; Hox-1.7, mouse, homolog of; HOX1; Hox1.7; Hox1G; Hox1r5; Hoxa-9; Hoxa7; HOXA9/MSI2 fusion gene, included; HOXA9/NUP98 fusion gene, included; HXA9_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 发育生物学  干细胞  转录调节因子  内皮细胞  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26, 30kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HOXA9
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
HOXA9 is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa 9 markedly expands hematopoietic stem cells. HOXA9 expression changes dramatically with age - a uniformly low level of expression during early adulthood is replaced by a frequently very high expression in adults over sixty.

Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 396096 Chicken

Entrez Gene: 100725915 Guinea pig

Entrez Gene: 3205 Human

Entrez Gene: 15405 Mouse

Entrez Gene: 500126 Rat

Omim: 142956 Human

SwissProt: Q98924 Chicken

SwissProt: P51783 Guinea pig

SwissProt: P31269 Human

SwissProt: P09631 Mouse

Unigene: 659350 Human

Unigene: 4694 Mouse

Unigene: 203714 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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