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Rabbit Anti-CA I/PE-Cy5 Conjugated antibody (bs-1592R-PE-Cy5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1592R-PE-Cy5
英文名称 Rabbit Anti-CA I/PE-Cy5 Conjugated antibody
中文名称 PE-Cy5标记的碳酸酐酶1抗体
别    名 Carbonic anhydrase I; Carbonic Anhydrase-I; Carbonic Anhydrase 1; Carbonic anhydrase1; Carbonic anhydrase-1; JW0122; CA 1; CA1; CA I; CA-1; CAI; CAN; Car 1; Car1; Carbonate dehydratase I; Carbonic anhydrase 1; Carbonic anhydrase B; Carbonic dehydratase; ECK0125; yadF; CAH1_MOUSE.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Cow, Rabbit, Sheep, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CA I
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature. [provided by RefSeq, Sep 2009]

Function:
Reversible hydration of carbon dioxide.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the alpha-carbonic anhydrase family.

Database links:

Entrez Gene: 759 Human

Entrez Gene: 12346 Mouse

Entrez Gene: 310218 Rat

Omim: 114800 Human

SwissProt: P00915 Human

SwissProt: P13634 Mouse

SwissProt: B0BNN3 Rat

Unigene: 23118 Human

Unigene: 273195 Mouse

Unigene: 6854 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CA1(Carbonic anhydrase1)是红细胞的主要蛋白质成分之一,是一种重要的锌酶,对血液及组织起到维持酸碱平衡的作用,协助体内组织排除二氧化碳,碳酸酐酶I参与呼吸、钙化、酸碱平衡、骨吸收和各种体液形成的生理过程。
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