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Rabbit Anti-CD82/Cy3 Conjugated antibody (bs-1470R-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1470R-Cy3
英文名称1 Rabbit Anti-CD82/Cy3 Conjugated antibody
中文名称 Cy3标记的肿瘤转移抑制蛋白1抗体
别    名 4F9; Antigen detected by monoclonal and antibody IA4; C33; C33 antigen; CD 82; CD82 antigen; CD82 molecule; GR 15; GR15; IA 4; IA4; Inducible membrane protein; Inducible membrane protein R2; KAI 1; KAI1; Kangai 1; Kangai1; Metastasis suppressor Kangai 1; Metastasis suppressor Kangai1; R2 leukocyte antigen; CD82_HUMAN.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  信号转导  转录调节因子  细胞表面分子  细胞类型标志物  t-淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD82
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.

Subunit:
Interacts directly with IGSF8.

Subcellular Location:
Membrane.

Tissue Specificity:
Lymphoid specific.

Similarity:
Belongs to the tetraspanin (TM4SF) family.

Database links:

Entrez Gene: 3732 Human

Entrez Gene: 12521 Mouse

Entrez Gene: 83628 Rat

Omim: 600623 Human

SwissProt: P27701 Human

SwissProt: P40237 Mouse

SwissProt: O70352 Rat

Unigene: 527778 Human

Unigene: 4261 Mouse

Unigene: 3022 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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