| 产品编号 | bs-1449R-AP |
| 英文名称1 | Rabbit Anti-Prohibitin/AP Conjugated antibody |
| 中文名称 | 碱性磷酸酶（AP）标记的抑制素/肿瘤抑制因子抗体 |
| 别 名 | Mitochondrial Marker; PHB; prohibitin; PHB1; Prohibitin - Mitochondrial Marker; PHB_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 染色质和核信号 细胞凋亡 细胞类型标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, (predicted: Dog, Horse, ) |
| 产品应用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 30kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Prohibitin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Function: Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. Subunit: Interacts with PHB2. Interacts with STOML2. Subcellular Location: Mitochondrion inner membrane. Tissue Specificity: Widely expressed in different tissues. Similarity: Belongs to the prohibitin family. Database links: Entrez Gene: 5245 Human Entrez Gene: 18673 Mouse Omim: 176705 Human SwissProt: P35232 Human SwissProt: P67778 Mouse Unigene: 514303 Human Unigene: 263862 Mouse Unigene: 29754 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Prohibitin(phb)基因是一种有效的肿瘤抑制基因，广泛分布于不同种属的各种生物细胞中，它所编码的产物Prohibitin(PHB)蛋白结构保守，既存在于线粒体内膜上，发挥分子伴侣作用，也存在于细胞核内，具有负性转录调控作用，因而对细胞代谢、生长、分化、衰老以及凋亡等诸多方面发挥 着重要的调控作用，可能与某些肿瘤和退行性疾病的发生有关。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
