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Rabbit Anti-IL-5/PE-Cy5 Conjugated antibody (bs-1318R-PE-Cy5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-1318R-PE-Cy5
英文名称 Rabbit Anti-IL-5/PE-Cy5 Conjugated antibody
中文名称 PE-Cy5标记的白细胞介素5抗体
别    名 B Cell Differentiation Factor I; IL5; IL 5; Colony stimulating factor; Colony Stimulating Factor Eosinophil; EDF; Eosinophil; Eosinophil Differentiation Factor; IL 5; Interleukin 5; B-cell differentiation factor I; IL-5; IL5_RAT; Interleukin-5; T Cell Replacing Factor; T-cell replacing factor; Interleukin5; TRF.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Rat,  (predicted: Mouse, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse IL-5
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Interleukin 5 is a cytokine produced primarily by activated T lymphocytes. It exists as an antiparallel disulfide linked homodimeric glycoprotein with 115 amino acid residues in each chain. Known also as EDF (eosinophil differentiating factor), functions predominantly as an eosinophilopoietic factor. Analysis of its crystal structure reveals a novel two domain structure, with each domain showing significant homology to the cytokine fold in GMCSF, MCSF, IL2, IL4 and growth hormone. Human and mouse IL5 have 70% amino acid sequence homology.

Function:
Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted.

Similarity:
Belongs to the IL-5 family.

Database links:

Entrez Gene: 3567 Human

Omim: 147850 Human

SwissProt: P05113 Human

Unigene: 2247 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

白细胞介素-5(IL-5)的表达对嗜酸粒细胞(EOS)有浸润聚集的作用,目前多用变态反应方面的研究。
支气管哮喘的重要特征主要是慢性非特异性炎症改变,其病因与发病机制十分复杂,白介素5在支气管哮喘发病机理上,近年来受到了很大关注。
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