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Rabbit Anti-BCAT1/PE-Cy7 Conjugated antibody (bs-6613R-PE-Cy7)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6613R-PE-Cy7
英文名称 Rabbit Anti-BCAT1/PE-Cy7 Conjugated antibody
中文名称 PE-Cy7标记的胞浆支链氨基酸酸转氨酶抗体
别    名 cytosolic; BCAT; BCAT(c); Bcat1; BCAT1_HUMAN; BCT1; Branched chain amino acid aminotransferase, cytosolic; Branched-chain-amino-acid aminotransferase; ECA39; MECA39; PNAS 121; Protein ECA39.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Sheep, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BCAT1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010].

Function:
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.

Subunit:
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
During embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma.

Similarity:
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

Database links:

Entrez Gene: 586 Human

Entrez Gene: 12035 Mouse

Omim: 113520 Human

SwissProt: P54687 Human

SwissProt: P24288 Mouse

Unigene: 438993 Human

Unigene: 4606 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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