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Rabbit Anti-TSPY1/FITC Conjugated antibody (bs-6607R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6607R-FITC
英文名称 Anti-TSPY1/FITC
中文名称 FITC标记的睾丸特异定蛋白质编码Y1抗体
别    名 DYS14; pJA 923; pJA923; Testis specific protein Y linked 1; Testis specific Y encoded protein 1; TSPY 1; TSPY; TSPY1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  发育生物学  染色质和核信号  干细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, )
产品应用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TSPY1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The function of this protein is unknown. TSPY genes are located on the Y-chromosome of several mammalian species. TSPY encodes a testis-specific protein 1, which probably acts as nucleosome-binding transcription factor. Homology with the SET/NAP/DENTT oncogene family suggest a role in spermatogonic cell division and seminal oncogenesis.

Function:
May be involved in sperm differentiation and proliferation.

Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus.

Tissue Specificity:
Specifically expressed in testicular tissues. Isoform 1 and isoform 2 are expressed in spermatogonia and spermatocytes. Found in early testicular carcinoma in situ, spermatogonial cells in testicular tissues of 46,X,Y female and in prostate cancer cell lines.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the nucleosome assembly protein (NAP) family.

Database links:
 

UniProtKB/Swiss-Prot: Q01534.4



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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