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Rabbit Anti-FSTL1/BF594 Conjugated antibody (bs-6050R-BF594)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-6050R-BF594
英文名称 Rabbit Anti-FSTL1/BF594 Conjugated antibody
中文名称 BF594标记的卵泡相关蛋白1
别    名 FSTL1; TSC-36; Follistatin like 1; Follistatin related protein; Follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; FSTL1; FSTL1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  细胞周期蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FSTL1/FRP
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
TSC-36 is a secreted extracellular glycoprotein. The amino acid sequence of TSC-36 is similar to follistatin, an inhibitor of activin, as it contains a follistatin module. TSC-36 is a heparin-binding protein suggested to have a role in the negative regulation of cellular growth, as its expression is induced in response to TGF-b1. In addition, TSC-36 is not found in small cell lung cancer (SCLC) cells, a highly aggressive neoplasm, but is detected in some non-small cell lung cancer (NSCLC) cells, a moderately aggressive neoplasm.. May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin.

Function:
May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin.

Subunit:
Interacts with SCN10A.

Subcellular Location:
Secreted.

Tissue Specificity:
Overexpressed in synovial tissues from rheumatoid arthritis.

Similarity:
Contains 2 EF-hand domains.
Contains 1 follistatin-like domain.
Contains 1 Kazal-like domain.
Contains 1 VWFC domain.

Database links:
 

 

Entrez Gene: 534482 Cow

Entrez Gene: 11167 Human

Entrez Gene: 14314 Mouse

Entrez Gene: 79210 Rat

Omim: 605547 Human

SwissProt: Q58D84 Cow

SwissProt: Q12841 Human

SwissProt: Q62356 Mouse

SwissProt: Q62632 Rat

Unigene: 269512 Human

Unigene: 182434 Mouse

Unigene: 95652 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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