产品编号 | IHC0647H |
英文名称 | Human Collagen I Ready-To-Use IHC Kit |
中文名称 | 人I型胶原即用型免疫组化试剂盒 |
别 名 | AA960264; AI325291; Col1a-1; Col1a-2; COL1A1; COL1A2; Cola-1; Cola-2; Cola1; Cola2; COLIA1; EDSC; I79_010913; Mov-13; Mov13; OI1; OI2; OI3; OI4; oim; Alpha 1 type I collagen; Collagen alpha 1(I) chain; collagen type I; alpha 1 |
适用样品基质 | FFPE tissue |
保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
产品介绍 |
Collagen I is a Type I collagen with a triple helix structure comprised of two alpha-1 chains and one alpha-2 chain. Collagen I is a member of group I collagen (fibril-forming collagen) found in most connective tissues, and is abundant in bone, cornea, dermis and tendon. Mutations in the COL1A2 gene encoding the alpha-2 chain are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in the COL1A2 gene which codes for the alpha-2 chain, however, tend to be less severe than mutations in the COL1A1 gene, reflecting the different role of alpha-2 chains in matrix integrity. Reciprocal translocations between chromosomes 17 and 22, where Collagen Type 1 genes and the gene for platelet derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified. SWISS: P02452 Gene ID: 1277 |
产品图片 |
Immunohistochemical analysis of paraffin embedded Human prostatic acinar adenocarcinoma tissue slide using IHC0647H (Human Collagen I Kit).
Immunohistochemical analysis of paraffin embedded Human prostate tissue slide using IHC0647H (Human Collagen I Kit).
Immunohistochemical analysis of paraffin embedded Human colon cancer tissue slide using IHC0647H (Human Collagen I Kit).
Immunohistochemical analysis of paraffin embedded Human uterus tissue slide using IHC0647H (Human Collagen I Kit).
Immunohistochemical analysis of paraffin embedded Human placenta tissue slide using IHC0647H (Human Collagen I Kit).
Immunohistochemical analysis of paraffin embedded Human kidney tissue slide using IHC0647H (Human Collagen I Kit).
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1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |