| 产品编号 | IHC0644H |
| 英文名称 | Human DCP1A Ready-To-Use IHC Kit |
| 中文名称 | 人脱帽酶1A即用型免疫组化试剂盒 |
| 别 名 | 1110066A22Rik; 4930568L04Rik; AU019772; D14Ertd817e; DCP1A; HSA275986; Mitc1; Nbla00360; DCP1 decapping enzyme homolog A; Dcp1a; DCP1A_HUMAN; mRNA decapping enzyme 1A; mRNA-decapping enzyme 1A; Smad4 interacting transcriptional co activator; Smad4-interacting transcriptional co-activator; Smad4-interacting transcriptional co-activator; SMAD4IP1; SMIF; Transcription factor SMIF |
| 适用样品基质 | FFPE tissue |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 产品介绍 |
Signal transduction of TGF-beta superfamily members is regulated by Smad proteins. In particular, Smads influence specific gene transcription by relaying signals from the cell membrane to the nucleus. Smad4 plays an essential role in TGF-beta-induced transcriptional activation wherein phosphorylated receptor-associated Smads associate with Smad4. Furthermore, SMIF (Smad4-intereacting protein) and Smad4 complex with TGF-beta and BMP4. An increase in Smad4 concentration increases the translocation of this complex to the nucleus. SMIF and Smad4 interact directly through a EVH1/WH1 domain on SMIF and a proline-rich activation domain on Smad4. Smad4 is essential to nuclear translocation of SMIF as deletion of the Smad4-interacting domain (located in the N-terminal 100 amino acids) of SMIF eliminates TGF-beta-induced nuclear translocation of SMIF. The human SMIF gene is ubiquitously expressed and encodes a protein with a relative molecular mass of 70 kDa. SWISS: Q9NPI6 Gene ID: 55802 |
| 产品图片 |
Immunohistochemical analysis of paraffin embedded Human kidney tissue slide using IHC0644H (Human DCP1A Kit).
Immunohistochemical analysis of paraffin embedded Human testis tissue slide using IHC0644H (Human DCP1A Kit).
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
