产品编号 | IHC0617H |
英文名称 | Human HLA-DPB1 Ready-To-Use IHC Kit |
中文名称 | 人组织相容性复合体2即用型免疫组化试剂盒 |
别 名 | DPB1; HLA-DP; HLA-DP1B; HLA-DPB; HLA-DPB1; HLA-DPB; major histocompatibility complex; class II; DP beta 1 |
适用样品基质 | FFPE tissue |
保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
产品介绍 |
HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry. SWISS: P04440 Gene ID: 3115 |
产品图片 |
Immunohistochemical analysis of paraffin embedded Human prostate cancer tissue slide using IHC0617H (Human HLA-DPB1 Kit).
Immunohistochemical analysis of paraffin embedded Human colon cancer tissue slide using IHC0617H (Human HLA-DPB1 Kit).
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1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |