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Human STING1 Ready-To-Use IHC Kit (IHC0614H)  
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50T/3200.00元
大包装/询价

产品编号 IHC0614H
英文名称 Human STING1 Ready-To-Use IHC Kit
中文名称 人跨膜蛋白173即用型免疫组化试剂盒
别    名 SAVI; STING1; TMEM173; endoplasmic reticulum IFN stimulator; Endoplasmic reticulum interferon stimulator; ERIS; FLJ38577; hMITA; hSTING; Mediator of IRF3 activation; MITA; Mitochondrial mediator of IRF3 activation; MPYS; N terminal methionine proline tyrosine serine plasma membrane tetraspanner; NET23; Stimulator of interferon genes; Stimulator of interferon genes protein; STING; TM173_HUMAN; Tmem173; Transmembrane protein 173  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. STING may have translocon function, the translocon possibly being able to influence the induction of type I interferons and is also involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II) thus facilitating the detection of intracellular viral RNA species as well as B-form DNA and mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. Generally seen in endoplasmic reticulum membrane, cell membrane and mitochondrion outer membrane, it is ubiquitously expressed in most of tissues.

产品图片
Immunohistochemical analysis of paraffin embedded Human prostate cancer tissue slide using IHC0614H (Human STING1 Kit).
Immunohistochemical analysis of paraffin embedded Human ovarian cancer tissue slide using IHC0614H (Human STING1 Kit).
Immunohistochemical analysis of paraffin embedded Human colon cancer tissue slide using IHC0614H (Human STING1 Kit).
Immunohistochemical analysis of paraffin embedded Human colon tissue slide using IHC0614H (Human STING1 Kit).
Immunohistochemical analysis of paraffin embedded Human tonsil tissue slide using IHC0614H (Human STING1 Kit).
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