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Mouse PSMD14 Ready-To-Use IHC Kit (IHC0602M)  
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50T/3200.00元
大包装/询价

产品编号 IHC0602M
英文名称 Mouse PSMD14 Ready-To-Use IHC Kit
中文名称 小鼠蛋白酶调解因子14即用型免疫组化试剂盒
别    名 2610312C03Rik; 3200001M20Rik; AA986732; PAD1; POH1; PSMD14; rpm11; RPN11  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 The 26S proteasome is responsible for most intracellular proteolysis in eukaryotes. POH1 (also known as Rpn11 in yeast) subunit of the 19S complex is responsible for substrate deubiquitination during proteasomal degradation. POH1 appears to be a Zn21-dependent protease, unlike all other known deubiquitinating enzymes (DUBs) that are cysteine proteases. POH1 was first identified as the human functional homolog of the S. pombe pad1 gene, which confers moderate resistance to chemotherapeutic drugs, and also to ultraviolet light when transiently overproduced in mammalian cells. Poh1-induced drug resistance is mediated through AP-1 transcription factors.

SWISS:
O00487

Gene ID:
10213

产品图片
Immunohistochemical analysis of paraffin embedded Mouse colon tissue slide using IHC0602M (Mouse PSMD14 Kit).
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