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产品中心-北京博奥森生物技术有限公司
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Rat JAK1 Ready-To-Use IHC Kit (IHC0565R)  
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50T/3200.00元
大包装/询价

产品编号 IHC0565R
英文名称 Rat JAK1 Ready-To-Use IHC Kit
中文名称 大鼠蛋白质酪氨酸激酶JAK-1即用型免疫组化试剂盒
别    名 AA960307; BAP004; C130039L05Rik; JAK 1; JAK 1A; JAK 1B; JAK1; JAK1A; JAK1B; Janus kinase 1 (a protein tyrosine kinase); Janus kinase 1; JTK3; Tyrosine protein kinase JAK 1; Tyrosine protein kinase JAK1; JAK1_HUMAN  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha/beta and -gamma signal transduction pathways. Immunological stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK1. JAK1 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription. Upon ligand binding, JAK1 undergoes tyrosine phosphorylation and catalytic activation in an interdependent manner. Phosphorylation of tyrosine residues at positions 1022 and 1023 is believed to function in the activation of catalytic events.

SWISS:
P23458

Gene ID:
3716

产品图片
Immunohistochemical analysis of paraffin embedded Rat kidney tissue slide using IHC0565R (Rat JAK1 Kit).
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