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GAD65 Ready-To-Use IHC Kit (IHC0528)  
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50T/3200.00元
大包装/询价

产品编号 IHC0528
英文名称 GAD65 Ready-To-Use IHC Kit
中文名称 谷氨酸脱羧酶-65即用型免疫组化试剂盒
别    名 6330404F12Rik; GAD(65); Gad-2; GAD2; GAD65  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 GAD65 (glutamic acid decarboxylase-65) are present in autoimmune disorders such as insulin-dependent (type1) diabetes mellitus (IDDM), stiff man syndrome and polyendocrine autoimmune disease. Auto-antibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM and thus are important markers for disease activity. These auto-antibodies usually recognize conformation-dependent regions on GAD65 and rarely bind to the second isoform, GAD67. Auto-antibodies to GAD67 are found in only 15% of recent-onset IDDM patients and most of this binding can be blocked with GAD65, suggesting shared epitopes between the two isoforms of GAD.

SWISS:
P48320

Gene ID:
14417

产品图片
Immunohistochemical analysis of paraffin embedded Mouse brain tissue slide using IHC0528 (GAD65 Kit).
Immunohistochemical analysis of paraffin embedded Rat brain tissue slide using IHC0528 (GAD65 Kit).
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