产品编号 |
IHC0527M |
英文名称 |
Mouse LY75 Ready-To-Use IHC Kit
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中文名称 |
小鼠淋巴细胞抗原75(CD205)即用型免疫组化试剂盒 |
别 名 |
CD205; CLEC13B; DEC-205; GP200-MR6; LY-75; LY75 |
适用样品基质 |
FFPE tissue |
保存条件 |
Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
产品介绍 |
CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
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产品图片 |
Immunohistochemical analysis of paraffin embedded Mouse spleen tissue slide using IHC0527M (Mouse LY75 Kit).
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