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Human p21 Ready-To-Use IHC Kit (IHC0519H)  
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50T/3200.00元
大包装/询价

产品编号 IHC0519H
英文名称 Human p21 Ready-To-Use IHC Kit
中文名称 人p21蛋白即用型免疫组化试剂盒
别    名 CAP20; CDKN1; CDKN1A; CIP1; MDA-6; MDA6; P21; p21CIP1; PIC1; SDI1; WAF1  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
产品介绍 Protein p21 is a tumor suppressor protein which is an inhibitor of Cyclin-dependent kinases (CDK) and is transcriptionally activated by p53. P21 is important in the response of cells to genotoxic stress and a major transcriptional target of p53 protein. The occurrence of p21 in the nucleus executes binding and inhibition activity of cyclin dependent kinases Cdk1 and Cdk2, and blocks the transition from G1 phase into S phase or from G2 phase into mitosis after DNA damage, which enables the repair of damaged DNA. In the cytoplasm, p21 protein has an anti-apoptotic effect. P21 is able to bind to and inhibit caspase 3, as well as the apoptotic kinases ASK1 and JNK. P21 exhibits a dual function in carcinogenesis, and acts as a tumor suppressor, prevents apoptosis, and acts as an oncogene.

SWISS:
P38936

Gene ID:
1026

产品图片
Immunohistochemical analysis of paraffin embedded Human colon cancer tissue slide using IHC0519H (Human p21 Kit).
Immunohistochemical analysis of paraffin embedded Human cervical cancer tissue slide using IHC0519H (Human p21 Kit).
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