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Recombinant human CNTF protein (Active, E.coli) (bs-48074P)  
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产品编号 bs-48074P
英文名称 Recombinant human CNTF protein (Active, E.coli)
中文名称 重组人睫状神经营养因子
别    名 Ciliary neurotrophic factor;  
克 隆 号
理论分子量 22.9 kDa
检测分子量
性    状 Lyophilized
纯    度 ≥ 95% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a 0.22μm-filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4
保存条件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 8℃ under sterile conditions after reconstitution
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. In addition to the predominant monocistronic transcript originating from this locus, the gene is also transcribed as a readthrough transcript with the upstream Zfp91 gene. The resulting protein is an isoform of Zfp91 and does not include Cntf sequence. Readthrough transcription of Zfp91 and Cntf has been observed in human and mouse.

SWISS:
Q6NTB0

Gene ID:
1270

神经干细胞标志物 有学者认为:睫状神经营养因子能促进运动神经轴突再生,CNTF可以阻止损伤后的运动神经元的退形性变性,目前CNTF对神经营养作用还在深入的研究中。
产品图片
Measured in a cell proliferation assay using TF-1 cells. The ED50 is
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