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Recombinant human PDGF-BB protein (Active, CHO) (bs-48071P)  
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产品编号 bs-48071P
英文名称 Recombinant human PDGF-BB protein (Active, CHO)
中文名称 重组人血小板衍生生长因子-BB
别    名 PDGFBB;  
克 隆 号
理论分子量 12.2 kDa
检测分子量
性    状 Lyophilized
纯    度 ≥ 95% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a 0.22μm filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH7.4
保存条件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 8℃ under sterile conditions after reconstitution
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. [SUBUNIT] Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. Belongs to the PDGF/VEGF growth factor family.

SWISS:
P01127

Gene ID:
5155

生长因子和激素( Growth Factor and Hormones) PDGF(platelet-dirived growth factor)是一种碱性蛋白,分为两个亚基(A、B链)通过二硫键结合而成的两条多肽链的异二聚体,分子量为28-35kDa。为促细胞分裂剂,可使小鼠成纤维细胞及其他多种细胞增殖。最新研究发现了PDGF家族两种新的基因PDGF-C、PDGF-D。
产品图片
Measured in a cell proliferation assay using NIH3T3 mouse embryonic fibroblast cells. The ED50 for this effect is ≤5 ng/mL.
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