| 产品编号 | bs-48057P |
| 英文名称 | Recombinant human IL-21 protein (Active, CHO) |
| 中文名称 | 重组人白细胞介素21 |
| 别 名 | Interleukin-21; Za11; IL21; |
| 克 隆 号 | |
| 理论分子量 | 15.9 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 纯 度 | ≥ 95% as determined by SDS-PAGE. |
| 缓 冲 液 | PBS, 5% Mannitol and 0.01% Tween 80 (pH=7.4) |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 8℃ under sterile conditions after reconstitution |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
IL-21 is a typical family I cytokine with broad pleiotropic actions and is primarily produced by T follicular helper cells, Th17, and natural killer T cells in response to antigenic stimulation. Il-21 generally enhances antigen-specific responses of immune cells. It controls the activation, proliferation, differentiation, cytotoxicity, and survival of various target immune cells. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 elicits its effect through binding to IL-21R, which also contains the gamma chain found in other cytokine receptors such as IL-2, IL-4, IL-7, IL-9 and IL-15. IL-21/IL-21R interaction triggers a cascade of events, which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant Human IL-21 is a 15.4 kDa protein consisting of 132 amino acid residues. SWISS: Q9HBE4 Gene ID: 59067 白介素21是多效免疫调节活性的细胞因子,与其受体结合后可以调节并促进B细胞、T细胞、NK细胞的增殖、分化并提高NK细胞杀伤活性。 |
| 产品图片 |
The purity of the protein is greater than 95% as determined by reducing SDS-PAGE.
Measured by its ability to enhance IFN-gamma secretion in NK-92 human natural killer lymphoma cells. The ED50 for this effect is ≤20 ng/mL.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
