| 产品编号 | bs-48056P |
| 英文名称 | Recombinant human IL-18 protein (Active, E.coli) |
| 中文名称 | 重组人白细胞介素18 |
| 别 名 | Interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma;GIF; IL-1g; IL1F4; MGC12320 |
| 克 隆 号 | |
| 理论分子量 | 18.2 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 纯 度 | ≥ 95% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from 0.22μm-filtered solution in PBS, 5% mannital, 0.01% Tween 80, pH7.4 |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 8℃ under sterile conditions after reconstitution |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. SWISS: Q14116 Gene ID: 3606 IL-18是巨噬细胞分泌的一个重要因子，它具有多种免疫功能，能诱导产生ＩＦＮγ，无论在病毒感染早期或特异性细胞免疫应答效应阶段都会出现，因此IL-18主要参与免疫应答及炎性细胞浸润的改变。Interleukin-18 又称inteferon-gamma inducing factor(IGIF)，在辅助T细胞的应答反应中起重要作用。IL-18和IL-1一起，既参与先天免疫，又是后天免疫的构成因素。 |
| 产品图片 |
Measured by its ability to induce IFN-gamma secretion by KG‑1 human acute myelogenous leukemia cells in the presence of TNF-alpha. The ED50 for this effect is ≤2.0 ng/mL.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
