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产品中心-北京博奥森生物技术有限公司
Recombinant human IL-1A protein (Active, E.coli) (bs-48053P)  
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产品编号 bs-48053P
英文名称 Recombinant human IL-1A protein (Active, E.coli)
中文名称 重组人白细胞介素1A
别    名 Interleukin-1 Alpha; IL-1 Alpha; Hematopoietin-1; IL1A; IL1F1; IL-1a;  
克 隆 号
理论分子量 18 kDa
检测分子量
性    状 Lyophilized
纯    度 ≥ 95% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a 0.22μm filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4
保存条件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 8℃ under sterile conditions after reconstitution
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin 1 alpha (IL1 alpha) and interleukin 1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.

SWISS:
P01583

Gene ID:
3552

IL-1α主要由胶原细胞产生。
产品图片
Measured by its ability to induce NF-kB reporter activity by the reporter gene assay. The ED50 for this effect is ≤0.05 ng/ml.
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