产品编号 | IHC0488H |
英文名称 | Human P4HB Ready-To-Use IHC Kit |
中文名称 | 人蛋白质二硫键异构酶即用型免疫组化试剂盒 |
别 名 | CLCRP1; DSI; ERBA2L; ERp59; GIT; P4HB; P4Hbeta; PDI; PDIA1; PDIR; PHDB; PO4DB; PO4HB; PROHB; Thbp |
适用样品基质 | FFPE tissue |
保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
产品介绍 |
Protein disulfide isomerase (PDI) is a multifunctional protein that catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, the protein seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. It may therefore cause structural modifications of exofacial proteins. Inside the cell, PDI seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, it functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, it facilitates aggregation (anti-chaperone activity). PDI may be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. It also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration. SWISS: P07237 Gene ID: 5034 |
产品图片 |
Immunohistochemical analysis of paraffin embedded human renal carcinoma tissue slide using IHC0488H (Human P4HB IHC Kit).
Immunohistochemical analysis of paraffin embedded human breast cancer tissue slide using IHC0488H (Human P4HB IHC Kit).
Immunohistochemical analysis of paraffin embedded human liver tissue slide using IHC0488H (Human P4HB IHC Kit).
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1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |