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ENPEP Recombinant Rabbit mAb (bsm-54646R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-54646R
英文名称 ENPEP Recombinant Rabbit mAb
中文名称 氨肽酶A重组兔单抗
别    名 Aminopeptidase A; AMPE_HUMAN; AP-A; APA; CD249; CD 249; Differentiation antigen gp160; EAP; EC 3.4.11.7; BP1; Glutamyl aminopeptidase; Gp160; Ly51; Ly51/6C3 antigen.  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号 11B3
交叉反应 (predicted: Human)
产品应用 WB=1:500-2000,IHC-P=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 109 kDa
检测分子量
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ENPEP 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Aminopeptidase A, also designated APA, gp160 human kidney differentiation antigen, glutamyl aminopeptidase, or enpep, is a differentiation-related kidney glycoprotein. As a cell surface, zinc-dependent metalloprotease, Aminopepti-dase A specifically cleaves amino-terminal acidic residues from peptide substrates such as Angiotensin II. APA is expressed on the surface of epithelial cells of the glomerulus and proximal tubule cells of the human nephron, where it may mediate the constitutive trafficking of Glut4-containing vesicles. These Glut4-containing vesicles are tissue-specific secretory-like microsomal structures that mediate insulin-dependent translocation of GLUT4 to the cell surface in fat and muscle cells. Mutations in the gp160/APA gene, including loss of protein expression or enzymatic activity, occur in 20% of primary clear cell renal carcinomas.

SWISS:
Q07075

Gene ID:
2028

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