| 产品编号 |
bs-105770P |
| 英文名称 |
Recombinant Mouse IL12A/IL-12 p35/NKSF1 Protein, C-His
|
| 中文名称 |
|
| 别 名 |
IL-12A, NK cell stimulatory factor chain 1, IL12A, CLMF p35, Interleukin-12 subunit alpha, IL-12 subunit p35, NKSF1, Cytotoxic lymphocyte maturation factor 35 kDa subunit |
| 理论分子量 |
25.15 kDa |
| 检测分子量 |
|
| 性 状 |
Lyophilized |
| 纯 度 |
>90% as determined by SDS-PAGE. |
| 缓 冲 液 |
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
bs-0767P is one synthetic peptide derived from mouse IL-12. IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
IL-12是新近发现的细胞因子，具有多种生物学活性，尤其是在抗肿瘤免疫和抗病毒免疫中有重要的作用。
|
|
|
