产品编号 | bs-105738P |
英文名称 | Recombinant Human UBB Protein, N-His |
中文名称 | |
别 名 | Polyubiquitin-B, UBB |
理论分子量 | 10.87 kDa |
检测分子量 | |
性 状 | Lyophilized |
纯 度 | >90% as determined by SDS-PAGE. |
缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] SWISS: P62988 Gene ID: 7314 泛素及类泛素蛋白(Ubls) 存在在多种细胞中,有多种细胞调控的功能,如细胞增殖、凋亡、细胞周期及DNA修复等。但泛素途径的异常会导致人类疾病的产生,包括多种形式的肿瘤的发生,神经退变等都与泛素有关。 相关产品: Ubiquitin 1-76 peptides (bs-10803P); |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |