| 产品编号 | bs-105719P |
| 英文名称 | Recombinant Human Hom s 5/KRT6A Protein, N-His |
| 中文名称 | |
| 别 名 | Cytokeratin-6A, Hom s 5, KRT6D, CK-6D, Cytokeratin-6D, K6A, Type-II keratin Kb6, Keratin-6A, KRT6A, Keratin, type II cytoskeletal 6A, CK-6A |
| 理论分子量 | 37.91 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]. SWISS: P48668 Gene ID: 3854 结构蛋白（Structural Proteins）细胞角蛋白是一类与结构相关的蛋白家族，其在上皮细胞中形成细胞骨架中间丝。CK6表达于鳞状上皮细胞，特别是增生的鳞状上皮。76%的脑、颈部鳞状细胞癌病例中有CK6的表达。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
