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产品中心-北京博奥森生物技术有限公司
Recombinant Human NPY Protein, N-His-SUMO (bs-105713P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-105713P
英文名称 Recombinant Human NPY Protein, N-His-SUMO
中文名称
别    名 Pro-neuropeptide Y, CPON, NPY, Neuropeptide tyrosine  
理论分子量 20.61 kDa
检测分子量
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]

Gene ID:
4852

神经生物学相关蛋白 神经肽Y是一种神经传导因子,参与机体的应急反应, 在应激状态下-NPY升高;他还可以促进血小板聚集、白细胞粘附及 巨噬细胞活化而参 与免疫反应 神经肽Y广泛分布于动物中枢和外周神经元及机体组织、器官和腺体内 ,影响动物采食、激素分泌、心血管效应、调节体温、生物节律、性行为及动物情绪等多种功能。 由于结构中富含酪氨酸 ,故称为神经肽酪氨酸 (NPY)。它的结构与同是 36个氨基酸的胰多肽 (pp)和肽 YY(PYY)极其相似 ,故认为同属胰多肽家族。从分子结构看 ,人、大鼠、豚鼠和兔序
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