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产品中心-北京博奥森生物技术有限公司
Recombinant Human CD304/NRP1 Protein, C-His (bs-105694P)  
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20ug/1280.00元
50ug/2580.00元
100ug/4180.00元
大包装/询价
产品编号 bs-105694P
英文名称 Recombinant Human CD304/NRP1 Protein, C-His
中文名称
别    名 NRP1, Neuropilin-1, VEGF165R, NRP, CD304, Vascular endothelial cell growth factor 165 receptor  
理论分子量 71.56 kDa
检测分子量
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

SWISS:
Q5T7F3

Gene ID:
8829

CD304是一种神经元受体,被认为表达于众多的非造血细胞上,包括神经元、内皮细胞和肿瘤细胞。在体外单核细胞和造血前体细胞衍生的CD1a+树突状细胞是CD304(BDCA-4/Neuropilin-1)。 与CD303(BDCA-2)一样,CD304(BDCA-4)抗原特异性地表达于人血液和骨髓中的浆样树突状细胞。与CD303(BDCA-2)不同的是,CD304(BDCA-4)在培养的浆样树突状细胞上表达上调,同时在培养的髓系细胞能被诱导表达。在感染的扁桃体中,CD304(BDCA-4)不仅表达于
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