产品编号 | bs-105694P |
英文名称 | Recombinant Human CD304/NRP1 Protein, C-His |
中文名称 | |
别 名 | NRP1, Neuropilin-1, VEGF165R, NRP, CD304, Vascular endothelial cell growth factor 165 receptor |
理论分子量 | 71.56 kDa |
检测分子量 | |
性 状 | Lyophilized |
纯 度 | >90% as determined by SDS-PAGE. |
缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011] SWISS: Q5T7F3 Gene ID: 8829 CD304是一种神经元受体,被认为表达于众多的非造血细胞上,包括神经元、内皮细胞和肿瘤细胞。在体外单核细胞和造血前体细胞衍生的CD1a+树突状细胞是CD304(BDCA-4/Neuropilin-1)。 与CD303(BDCA-2)一样,CD304(BDCA-4)抗原特异性地表达于人血液和骨髓中的浆样树突状细胞。与CD303(BDCA-2)不同的是,CD304(BDCA-4)在培养的浆样树突状细胞上表达上调,同时在培养的髓系细胞能被诱导表达。在感染的扁桃体中,CD304(BDCA-4)不仅表达于 |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |