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产品中心-北京博奥森生物技术有限公司
Recombinant Human HTR2A Protein, N-His (bs-105163P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-105163P
英文名称 Recombinant Human HTR2A Protein, N-His
中文名称
别    名 5-HT-2A; 5-hydroxytryptamine receptor 2A; Serotonin receptor 2A; HTR2A; 5-HT-2; HTR2  
克 隆 号
理论分子量 18.6 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 5HT2A receptor is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. 5HT2A receptor belongs to the G-protein coupled receptor 1 family and mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. 5HT2A receptor is an integral membrane protein which localizes to the post-synaptic thickening of axo-dendritic synapses. 5HT2A receptor protein contains a PDZ domain-binding motif which is involved in the interaction with INADL, CASK, APBA1, DLG1 and DLG4.

SWISS:
P28223

Gene ID:
3356

5-HT2A受体位于大脑皮层第4层内,参与磷酸肌醇的水解。 5-HTR2A受体与睡眠有密切关系. 也有学者认为:5-HT2A受体与精神分裂症及脑神经退行性改变有关。5-HT2A受体可能成为非典型抗精神病药物作用的靶受体。
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