| 产品编号 | bs-105147P |
| 英文名称 | Recombinant Human BCL2L11 Protein, N-His-SUMO |
| 中文名称 | |
| 别 名 | BCL2L11; Bcl-2-like protein 11; Bcl2-interacting mediator of cell death; BIM; Bcl2-L-11 |
| 克 隆 号 | |
| 理论分子量 | 22.31 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Bim, Bcl-2 interacting mediator of cell death, is a pro-apoptotic protein belonging to the Bcl2 family of proteins containing a Bcl2 homology domain 3 (BH3). It is proapoptotic and exerts its effects by interacting with prosurvival members of the Bcl2 family like Bcl2, BclxL and Bclw. Bim is sequestered in an inactive conformation through binding to the microtubule-associated dynein motor complex. Certain apoptotic stimuli release Bim from microtubules, allowing inhibitory binding to anti-apoptotic Bcl-2 family members and subsequent iniation of apoptosis. SWISS: O43521 Gene ID: 10018 Bim是Bcl-2家族BH3-only亚家族的成员,是一种重要的凋亡调节蛋白，具有助凋亡活性作用。Bim广泛表达于正常细胞,对防御自身免疫、维持造血细胞稳态有重要意义,并具有肿瘤抑制因子活性.Bim的生理作用与它调节细胞凋亡的功能有关。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
