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产品中心-北京博奥森生物技术有限公司
Recombinant Human CASPR2/CNTNAP2 Protein, N-His (bs-105125P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-105125P
英文名称 Recombinant Human CASPR2/CNTNAP2 Protein, N-His
中文名称
别    名 Contactin-associated protein-like 2; Cell recognition molecule Caspr2; CNTNAP2; CASPR2; KIAA0868  
克 隆 号
理论分子量 139.16 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 bs-11129P is one synthetic peptide derived from human Caspr2. CASPR is a transmembrane glycoprotein of the neurexin superfamily that is highly enriched in regions of myelinated axons. The axons of myelinated nerves in the adult nervous system possess specialized subcellular structures essential for efficient and rapid action potential propagation. CASPR and the closely related molecule CASPR2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. While CASPR is present at the paranodal junctions, CASPR2 is precisely colocalized with Shaker-like K+ channels in the juxtaparanodal region. CASPR2 specifically associates with Kv1.1, Kv1.2, and their Kvbeta2 subunit. CASPR family members may play a role in the local differentiation of the axon into distinct functional subdomains.

SWISS:
Q9UHC6

Gene ID:
26047

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