| 产品编号 | bs-105103P |
| 英文名称 | Recombinant Human PLAT/tPA (wt) Protein, C-His |
| 中文名称 | |
| 别 名 | Tissue-type plasminogen activator; t-PA; t-plasminogen activator; tPA; 3.4.21.68; Alteplase; Reteplase; Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B; PLAT |
| 克 隆 号 | |
| 理论分子量 | 63.51 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] SWISS: P00750 Gene ID: 5327 组织型纤溶酶原激活剂tPA是丝氨酸蛋白酶家族的一员,其主要的生物学功能是激活纤溶酶原转变为纤溶酶. 近年来经研究表明t-PA参与循环系统的溶血栓过程之外,t-PA还在神经系统中也发挥了重要的作用，t-PA参与了癫痫和早老型痴呆症等神经系统疾病的发生和发展，在学习和记忆等生理过程中也发挥了重要作用。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
