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Recombinant Human PGF/PlGF/PLGF Protein, N-His (bs-104979P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104979P
英文名称 Recombinant Human PGF/PlGF/PLGF Protein, N-His
中文名称
别    名 PLGF; PGF; PlGF; PGFL; Placenta growth factor  
克 隆 号
理论分子量 17.02 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The placental-derived growth factor (PIGF) is a dimeric glycoprotein showing a high degree of sequence similarity to the vascular endothelial growth factor. Alternative splicing of the PIGF primary transcript gives rise to two forms, named PIGF-1 and PIGF-2, which differ only in the insertion of a highly basic 21-amino acid stretch at the carboxyl end. The presence of the PIGF mRNA in thyroid, placenta, lung, and goiter has indicated the tissues where this factor functions. However, the role of PIGF in vascular development has not yet been clearly established.

SWISS:
P49763

Gene ID:
5228

PLGF胎盘生长因子是血管生长因子家族成员之一(又称:胎盘型血管内皮细胞生长因子),是动脉粥样硬化斑块不稳定的主要炎性激活物,因此它可作为ACS患者风险预测的生物学标志物.尿胎盘生长因子水平可预测先兆子痫危险.研究人员发现,在疾病发作前的6到8周,先兆子痫患者尿液中的胎盘生长因子水平急剧下降,这种新的尿检方法使提前1到2个月预测先兆子痫成为可能。亦有研究人员正在从事胎盘生长因子与肺气肿,胃癌,肠癌等方面的研究。
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