| 产品编号 | bs-104961P |
| 英文名称 | Recombinant Human F2/Prothrombin Protein, N-His |
| 中文名称 | |
| 别 名 | F2; Coagulation factor II; Prothrombin |
| 克 隆 号 | |
| 理论分子量 | 36.1 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Des-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. Normally, the prothrombin precursor undergoes post-translational carboxylation (addition of a carboxylic acid group) by gamma-glutamyl carboxylase in the liver prior to secretion into plasma. DCP/PIVKA-II may be detected in people with deficiency of vitamin K (due to poor nutrition or malabsorption) and in those taking warfarin or other medication that inhibits the action of vitamin K. SWISS: P00734 Gene ID: 2147 正常肝细胞中，在内质网内可将DCP羧化使之成为有活性的凝血酶原，一旦机体需要，凝血酶原即可转变成凝血酶参与机体的各项生理功能，当有肿瘤细胞发生时，DCP明显升高。DCP主要用于肝癌方面的研究；有学者认为：联合应用DCP和AFP对于早期诊断HCC（原发性肝细胞癌）有较大的帮助。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
