| 产品编号 | bs-104921P |
| 英文名称 | Recombinant Mouse CD354/TREM1 Protein, N-His |
| 中文名称 | |
| 别 名 | TREM1; Triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells 1; TREM-1; CD354 |
| 克 隆 号 | |
| 理论分子量 | 14.99 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]. SWISS: Q9JKE2 Gene ID: 58217 TREM-1是近年来发现应用于诊断炎症性疾病的重要标记物,也是感染性疾病的预警指标,与细菌感染的严重程度相关。TREM-1出现早,半衰期短,在早期炎症诊断中很有意义。 TREM 1属于免疫球蛋白超家族TREM,表达于白细胞的细胞膜表面受体,TREM-1选择性地表达于中性粒细胞和部分单核细胞, 它介导的信号传导通路在炎症的发生和级联放大中起重要作用。 TREM-1激活后可上调TNF-α和IL-1等细胞因子的表达,并抑制抗炎症反应因子IL-10的表达,同时它激活的细胞因子又能上调TREM-1的表达。TREM- |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
