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Recombinant Human WRAP53 Protein, N-His (bs-104862P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104862P
英文名称 Recombinant Human WRAP53 Protein, N-His
中文名称
别    名 WD repeat-containing protein 79; TCAB1; WD40 repeat-containing protein antisense to TP53 gene; Telomerase Cajal body protein 1; WRAP53; WRAP53beta; WDR79  
克 隆 号
理论分子量 30.63 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 WDR79 contains six WD (tryptophan-aspartate) repeat domains found in a number of proteins that function as adaptor molecules in signal transduction and cytoskeletal organization. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. The function of the WDR79 protein has not been characterized, however significant and consistent single nucleotide polymorphisms in the WDR79 gene have been found to be associated with ER negative breast cancer.

SWISS:
Q9BUR4

Gene ID:
55135

TCAB1是端粒酶的一个真正组成部分。但它对酶的活性来说并不是必需的,它只是给称为卡哈尔体(Cajalbodies)的细胞核中的处理和保持区域补充端粒酶复合物。卡哈尔体将对各种使用RNA小分子来引领其活性的蛋白进行修饰,譬如,端粒酶使用RNA分子作为嵌在染色体末端的DNA链的模板。在适当的时候,TCAB1将端粒酶复合物运送到新复制染色体的等待端。 研究人员认为,TCAB1蛋白可能是一种负责将各种分子运往其目的地的普通生物运输器。
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