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产品中心-北京博奥森生物技术有限公司
Recombinant Human TIGAR Protein, N-His (bs-104699P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104699P
英文名称 Recombinant Human TIGAR Protein, N-His
中文名称
别    名 Fructose-2; 6-bisphosphatase TIGAR; TP53-induced glycolysis and apoptosis regulator; TIGAR; C12orf5; TP53-induced glycolysis regulatory phosphatase  
克 隆 号
理论分子量 32.23 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq, Jul 2008]

SWISS:
Q9NQ88

Gene ID:
57103

TIGAR为TP53诱导糖酵解和凋亡调节因子 TIGAR的表达可以调整对p53的凋亡应答,主要用于肿瘤方面的研究。
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