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产品中心-北京博奥森生物技术有限公司
Recombinant Human PRMT1 Protein, N-His (bs-104695P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104695P
英文名称 Recombinant Human PRMT1 Protein, N-His
中文名称
别    名 IR1B4; Protein arginine N-methyltransferase 1; HRMT1L2; HMT2; Interferon receptor 1-bound protein 4; PRMT1; Histone-arginine N-methyltransferase PRMT1  
克 隆 号
理论分子量 38.25 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 PRMTs are a family of proteins that either monomethylate or dimethylate the guanidino nitrogen atoms of arginine side chains. PRMT1 methylates Histone H4 on R3 and acts synergistically with p300/CBP to enhance transcriptional activation by nuclear receptors. PRMT1 also methylates a number of non-histone proteins such as the orphan nuclear receptor HNF4, components of the heterogeneous nuclear ribonucleoprotein (hnRNP) particle, interleukin enhancer-binding factor 3 (ILF3), and interferon alpha and beta receptors. This suggests roles for PRMT1 in transcriptional regulation, mRNA processing and signal transduction. PRMT1 is also a coactivator for p53, methylating histone H4 to facilitate p53-mediated transcription.

SWISS:
Q99873

Gene ID:
3276

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