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产品中心-北京博奥森生物技术有限公司
Recombinant Human MTIF3 Protein, N-His (bs-104575P)  
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20ug/980.00元
50ug/1880.00元
100ug/2680.00元
大包装/询价
产品编号 bs-104575P
英文名称 Recombinant Human MTIF3 Protein, N-His
中文名称
别    名 IF-3(Mt); IF3mt; MTIF3; Translation initiation factor IF-3; mitochondrial; IF3(mt); IF-3Mt  
克 隆 号
理论分子量 20.99 kDa
性    状 Lyophilized
纯    度 >90% as determined by SDS-PAGE.
缓 冲 液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
保存条件 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 IF3 is also known as MTIF3 (mitochondrial translational initiation factor 3), DC38, IF3(mt) or IF-3mt, and is a 278 amino acid protein that is localized to mitochondria. IF3 aids in the initiation of protein synthesis by binding the 28S ribosomal subunit, which is a protein synthesis initiation site. The 28S and 39S ribosomal structures are subunits of the 55S ribosome, whose formation is favored in the absence of IF3, because IF3 allows the subunits to remain in their free form. Altered forms of IF3 may affect IF3’s function, which could alter the availability of mitochondrial encoded proteins, leading to oxidative stress and possibly causing an increased susceptibility to Parkinson’s disease. Polymorphism of the gene encoding IF3 is thought to be associated with Parkinson’s disease.

SWISS:
Q9H2K0

Gene ID:
219402

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