| 产品编号 | bs-104475P |
| 英文名称 | Recombinant Human MSH6 Protein, N-His |
| 中文名称 | |
| 别 名 | DNA mismatch repair protein Msh6; MutS protein homolog 6; MSH6; GTBP; hMSH6; GTMBP; G/T mismatch-binding protein; MutS-alpha 160 kDa subunit; p160 |
| 克 隆 号 | |
| 理论分子量 | 34.29 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013] SWISS: P52701 Gene ID: 2956 MSH6是DNA错配修复系统的基因组成之一。DNA错配修复系统由hMLH1，hMSH2，hPMS1，hPMS2，hMSH6和hMSH3等基因组成，这套系统的存在，可保证遗传物质的完整性和稳定性，避免遗传物质的突变产生，保证DNA复制的高保真度。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
