| 产品编号 | bs-104464P |
| 英文名称 | Recombinant Human IAPP Protein, N-His-SUMO |
| 中文名称 | |
| 别 名 | IAPP; Islet amyloid polypeptide; Diabetes-associated peptide; Insulinoma amyloid peptide; Amylin; DAP |
| 克 隆 号 | |
| 理论分子量 | 19.74 kDa |
| 性 状 | Lyophilized |
| 纯 度 | >90% as determined by SDS-PAGE. |
| 缓 冲 液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. SWISS: P10997 Gene ID: 3375 胰岛淀粉样肽(islet amyloid polypeptide,IAPP)又称amylin 或糖尿病相关肽是由胰腺β细胞产生的含37个氨基酸的一种短肽。IAPP降低胰岛素的敏感性，抑制肌肉组织中葡萄糖的摄取和糖原的合成，抑制病人摄取食物。 据报道胰腺癌病人血浆IAPP浓度显著升高，而在胃癌、结肠癌、肝癌、肺癌中正常，在糖尿病人中正常或稍低。由于血浆IAPP浓度上升是胰腺癌的一个早期特征，因而检测IAPP或IAPP释放因子对于胰腺癌的早期诊断是有价值的。但目前还不清楚IAPP释放 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
